Effect of one-month concurrent training with or without caffeine supplementation on resting energy expenditure and leptin resistance in overweight women

Background and Objective: Leptin resistance is an important risk factor for obesity. So, the present study was conducted in order to determine the effectiveness of one-month concurrent training with and without caffeine ingestion on the resting energy expenditure and leptin resistance in overweight women.   Materials and Methods: 20 non-athlete and overweight women in a double-blind and quasi-experimental designs in the two groups pre-post intervention (concurrent training group + placebo and concurrent training group + caffeine) for 4 weeks of a concurrent training (three sessions per week for 1.5 hours per session; aerobic training with an intensity between 65-85% heart rate reserve and resistance training with an intensity of 70-75% of one repetition maximum) with and without caffeine (5 mg.kg-1.day). Changes in resting energy expenditure and leptin resistance during two phases (baseline and 24 hours after completing the training period).   Results: Serum fasting leptin levels significantly reduced in both groups following one month period of concurrent training (p=0.04). However, there was no significant difference between the two groups. Also, caffeine supplementation administered together with concurrent training could increase resting expenditure energy (REE) and decrease leptin resistance index after one month (p=0.032).   Conclusion: Based on the findings of this study, it can be concluded that one month of aerobic-resistance concurrent training in both groups, especially with considering the further reduction of the indices studied in the caffeine consumer group; maybe prevent the risk factors associated with obesity in overweight women.